报告题目：Spatio-temporal dynamics of an age-space structured cholera model with bacterial hyperinfectivity and imperfect vaccination

工作单位：山西大学

报告时间：2023年11月15日（周三 9:00-10:30）

报告地点：腾讯会议 958-405-647

报告摘要：

Cholera is a waterborne disease caused by the bacterium Vibrio cholerae. Laboratory findings suggested that passage through the human host transiently increased the infection potential of the bacteria by creating a hyperinfectious bacterial state, which may contribute to the epidemic spread of cholera. In this talk, we are concerned with an infection age-space structured cholera model with multiple transmission pathways, hyperinfectious and hypoinfectious vibrios, imperfect vaccination, and distinct dispersal rates for humans in a general continuous bounded domain under Neumann boundary condition. By analyzing the corresponding characteristic equations and constructing suitable Lyapunov functionals, the basic reproduction number is determined as a threshold to predict whether the infection will persist. Numerical simulations are carried out to illustrate the theoretical results and suggest that compared with increasing the vaccination rate of susceptible humans, enhancing vaccine efficacy is more conducive to reducing the basic reproduction number and controlling cholera spread.

个人简介：

徐瑞：2005年英国Dundee大学数学生物学专业获哲学博士学位；现任山西大学复杂系统研究所教授、博士生导师。担任Elsevier出版社SCI期刊Mathematics and Computers in Simulation编委。先后主持完成和在研国家自然科学基金面上项目5项；科学出版社出版学术专著5部；在国际学术期刊发表SCI论文100余篇。入选2021年和2022年爱思唯尔“中国高被引学者”榜单。